Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CSNK1A1Casein kinase 1 alpha 1. (288 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
   
 0.996
AXIN1
Axin 1.
    
 0.995
AXIN2
Axin 2.
    
 0.991
GSK3B
Glycogen synthase kinase 3 beta.
    
 0.987
APC
APC regulator of WNT signaling pathway.
    
 0.983
JUP
Junction plakoglobin.
   
 0.971
PIP5K1A
Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha.
    
 0.969
CRBN
Cereblon.
    
 
 0.966
GSK3A
Glycogen synthase kinase 3 alpha.
    
 0.965
CSNK1D
Casein kinase 1 delta.
   
  0.965
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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