Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TFR2Transferrin receptor 2. (804 aa)    
Predicted Functional Partners:
HFE
Homeostatic iron regulator.
    
 0.998
HJV
Hemojuvelin BMP co-receptor.
     
 0.990
EPOR
Erythropoietin receptor.
    
 0.987
ENSCAPP00000006521
annotation not available
  
 0.963
BMPR1A
Bone morphogenetic protein receptor type 1A.
    
 0.925
TFRC
Transferrin receptor.
    
 0.924
LTF
Lactotransferrin.
  
 0.910
BMPR1B
Bone morphogenetic protein receptor type 1B.
    
 0.906
CSF3
Colony stimulating factor 3.
   
 
 0.900
ENSCAPP00000010105
annotation not available
     
 0.898
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (24%) [HD]