Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTPRUProtein tyrosine phosphatase receptor type U. (1428 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
    
 0.966
KIT
KIT proto-oncogene, receptor tyrosine kinase.
    
  0.935
PTPRE
Protein tyrosine phosphatase receptor type E.
    
 0.916
JUP
Junction plakoglobin.
    
 0.832
LRRC4
Leucine rich repeat containing 4.
   
 0.765
PPM1M
Protein phosphatase, Mg2+/Mn2+ dependent 1M.
      
 0.747
CSF1R
Colony stimulating factor 1 receptor.
    
  0.746
PTPRK
Protein tyrosine phosphatase receptor type K.
    
 0.736
PTPRM
Protein tyrosine phosphatase receptor type M.
   
   0.717
ENSCAPP00000001903
annotation not available
   
   0.717
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.