STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPRUProtein tyrosine phosphatase receptor type U. (1428 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
    
 0.796
KIT
KIT proto-oncogene, receptor tyrosine kinase.
    
  0.745
JUP
Junction plakoglobin.
    
 0.723
PTK7
Protein tyrosine kinase 7 (inactive).
    
 0.715
LRIT3
Leucine rich repeat, Ig-like and transmembrane domains 3.
    
  0.707
LRIT1
Leucine rich repeat, Ig-like and transmembrane domains 1.
    
  0.707
CSF1R
Colony stimulating factor 1 receptor.
    
  0.675
ROR2
Receptor tyrosine kinase like orphan receptor 2.
    
  0.652
ROR1
Receptor tyrosine kinase like orphan receptor 1.
    
  0.652
GRB2
Growth factor receptor bound protein 2.
   
 0.645
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.