Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RFFLRing finger and FYVE like domain containing E3 ubiquitin protein ligase. (384 aa)    
Predicted Functional Partners:
RNF34
Ring finger protein 34.
    
   0.957
ENSCAPP00000000972
annotation not available
    
 
 0.921
ENSCAPP00000008606
annotation not available
    
 
 0.921
ENSCAPP00000006804
annotation not available
    
   0.905
TP53
Tumor protein p53.
    
  0.873
SHC1
SHC adaptor protein 1.
    
   0.821
ENSCAPP00000018490
annotation not available
    
   0.812
DNAJB12
DnaJ heat shock protein family (Hsp40) member B12.
      
 0.773
PRKD2
Protein kinase D2.
    
   0.772
MYRF
Myelin regulatory factor.
      
 0.718
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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