STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPTLC3Serine palmitoyltransferase long chain base subunit 3. (475 aa)    
Predicted Functional Partners:
SPTLC1
Serine palmitoyltransferase long chain base subunit 1.
  
0.981
ORMDL3
ORMDL sphingolipid biosynthesis regulator 3.
    
 0.955
KDSR
3-ketodihydrosphingosine reductase.
     
 0.860
ORMDL1
ORMDL sphingolipid biosynthesis regulator 1.
    
 0.850
SORD
Sorbitol dehydrogenase.
  
 
 0.850
ENSCAPP00000011545
annotation not available
    
 0.848
SHMT2
Serine hydroxymethyltransferase 2.
  
 
 0.815
ENSCAPP00000018242
annotation not available
    
 0.813
PSPH
Phosphoserine phosphatase.
    
 0.809
AGXT
Alanine--glyoxylate and serine--pyruvate aminotransferase.
    
 0.809
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.