Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MTCP1Mature T cell proliferation 1. (104 aa)    
Predicted Functional Partners:
AKT1
AKT serine/threonine kinase 1.
    
 0.980
AKT3
AKT serine/threonine kinase 3.
    
 0.942
AKT2
AKT serine/threonine kinase 2.
    
 0.942
ENSCAPP00000011480
annotation not available
    
   0.672
MED10
Mediator complex subunit 10.
    
   0.622
MED28
Mediator complex subunit 28.
    
   0.622
ENSCAPP00000010970
annotation not available
    
   0.622
MED22
Mediator complex subunit 22.
    
   0.609
MED20
Mediator complex subunit 20.
    
   0.598
ENSCAPP00000011290
annotation not available
    
   0.597
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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