close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DENND4CDENN domain containing 4C. (1557 aa)    
Predicted Functional Partners:
ANKFY1
Ankyrin repeat and FYVE domain containing 1.
     
 0.972
DENND5A
DENN domain containing 5A.
    
0.960
VPS35
VPS35 retromer complex component.
    
  0.926
ENSCAPP00000018579
annotation not available
    
  0.924
RAB7A
RAB7A, member RAS oncogene family.
    
 0.923
DENND5B
DENN domain containing 5B.
    
0.910
RAB10
RAB10, member RAS oncogene family.
    
 0.654
RAB8A
RAB8A, member RAS oncogene family.
    
 0.580
RAB8B
RAB8B, member RAS oncogene family.
    
 0.580
MINDY1
MINDY lysine 48 deubiquitinase 1.
      
 0.551
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.