Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ITIH4Inter-alpha-trypsin inhibitor heavy chain 4. (858 aa)    
Predicted Functional Partners:
ITIH1
Inter-alpha-trypsin inhibitor heavy chain 1.
   
   0.913
HRG
Histidine rich glycoprotein.
   
 0.887
CP
Ceruloplasmin.
   
 0.886
HPX
Hemopexin.
   
 0.878
KNG1
Kininogen 1.
   
 0.877
ITIH2
Inter-alpha-trypsin inhibitor heavy chain 2.
   
    0.864
SERPIND1
Serpin family D member 1.
   
 
 0.859
ENSCAPP00000003824
annotation not available
   
 0.843
ENSCAPP00000015384
annotation not available
   
 
 0.815
AMBP
Alpha-1-microglobulin/bikunin precursor.
   
 
 0.794
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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