Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRAF4TNF receptor associated factor 4. (472 aa)    
Predicted Functional Partners:
USP7
Ubiquitin specific peptidase 7.
    
 0.974
TRAF2
TNF receptor associated factor 2.
   
 0.956
TRAF6
TNF receptor associated factor 6.
    
 
 0.953
SMURF2
SMAD specific E3 ubiquitin protein ligase 2.
    
 0.946
AKT1
AKT serine/threonine kinase 1.
    
 0.937
ENSCAPP00000015040
annotation not available
    
 0.927
ENSCAPP00000000633
annotation not available
    
 
 0.924
ISYNA1
Inositol-3-phosphate synthase 1.
    
   0.887
TRAF1
TNF receptor associated factor 1.
   
 0.884
ENSCAPP00000014603
annotation not available
    
  0.882
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.