STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH2B1SH2B adaptor protein 1. (754 aa)    
Predicted Functional Partners:
ENSCAPP00000013675
annotation not available
    
 0.982
JAK2
Janus kinase 2.
    
 0.981
INSR
Insulin receptor.
    
 0.974
GRB2
Growth factor receptor bound protein 2.
    
 0.964
CBLB
Cbl proto-oncogene B.
    
 0.952
NTRK1
Neurotrophic receptor tyrosine kinase 1.
    
 0.938
NTRK2
Neurotrophic receptor tyrosine kinase 2.
    
 0.911
ENSCAPP00000000757
annotation not available
    
 0.891
ENSCAPP00000016030
annotation not available
    
 0.891
SH2B3
SH2B adaptor protein 3.
    
 0.885
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.