STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH2B1SH2B adaptor protein 1. (754 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.954
INSR
Insulin receptor.
    
 0.924
ENSCAPP00000000757
annotation not available
    
 0.903
ENSCAPP00000016030
annotation not available
    
 0.903
JAK2
Janus kinase 2.
    
 0.900
NTRK1
Neurotrophic receptor tyrosine kinase 1.
    
 0.873
ENSCAPP00000013675
annotation not available
    
 0.865
NTRK2
Neurotrophic receptor tyrosine kinase 2.
    
 0.858
CBLB
Cbl proto-oncogene B.
    
 0.845
SH2B3
SH2B adaptor protein 3.
    
0.823
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.