Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NLRP3NLR family pyrin domain containing 3. (1006 aa)    
Predicted Functional Partners:
ENSCAPP00000004927
annotation not available
    
 0.997
ENSCAPP00000017531
annotation not available
    
 0.996
MAVS
Mitochondrial antiviral signaling protein.
    
 0.995
NEK6
NIMA related kinase 6.
    
 0.981
NLRC4
NLR family CARD domain containing 4.
   
 0.962
NFKB1
Nuclear factor kappa B subunit 1.
    
 0.948
ENSCAPP00000002506
annotation not available
    
 0.924
HSP90AA1
Heat shock protein 90 alpha family class A member 1.
    
 0.924
DHX33
DEAH-box helicase 33.
    
 0.920
ENSCAPP00000013044
annotation not available
    
   0.912
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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