Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TNFRSF25TNF receptor superfamily member 25. (408 aa)    
Predicted Functional Partners:
TRADD
TNFRSF1A associated via death domain.
    
 0.987
TNF
Tumor necrosis factor.
    
 0.955
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.910
LTA
Lymphotoxin alpha.
    
 0.886
ENSCAPP00000006795
annotation not available
    
 0.845
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.842
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
 0.838
NSMAF
Neutral sphingomyelinase activation associated factor.
    
 0.835
TOR1A
Torsin family 1 member A.
      
 0.812
ENSCAPP00000004807
annotation not available
    
 0.798
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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