NFE2L2 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NFE2L2

Nuclear factor, erythroid 2 like 2. (522 aa)

Predicted Functional Partners:

KEAP1

0.999

KLHL17

0.969

MAFG

0.965

EIF2AK3

0.943

MAFK

0.939

DDIT3

0.936

MAPK7

0.931

PARK7

0.930

KLHL18

0.930

ENSCAPP00000016515

0.927

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDIT3	EIF2AK3	ENSCAPP00000005759	ENSCAPP00000013660	DNA damage inducible transcript 3.	Eukaryotic translation initiation factor 2 alpha kinase 3.	0.532
DDIT3	ENSCAPP00000016515	ENSCAPP00000005759	ENSCAPP00000016515	DNA damage inducible transcript 3.	annotation not available	0.415
DDIT3	MAPK7	ENSCAPP00000005759	ENSCAPP00000012050	DNA damage inducible transcript 3.	Mitogen-activated protein kinase 7.	0.622
DDIT3	NFE2L2	ENSCAPP00000005759	ENSCAPP00000001397	DNA damage inducible transcript 3.	Nuclear factor, erythroid 2 like 2.	0.936
EIF2AK3	DDIT3	ENSCAPP00000013660	ENSCAPP00000005759	Eukaryotic translation initiation factor 2 alpha kinase 3.	DNA damage inducible transcript 3.	0.532
EIF2AK3	ENSCAPP00000016515	ENSCAPP00000013660	ENSCAPP00000016515	Eukaryotic translation initiation factor 2 alpha kinase 3.	annotation not available	0.806
EIF2AK3	NFE2L2	ENSCAPP00000013660	ENSCAPP00000001397	Eukaryotic translation initiation factor 2 alpha kinase 3.	Nuclear factor, erythroid 2 like 2.	0.943
ENSCAPP00000016515	DDIT3	ENSCAPP00000016515	ENSCAPP00000005759	annotation not available	DNA damage inducible transcript 3.	0.415
ENSCAPP00000016515	EIF2AK3	ENSCAPP00000016515	ENSCAPP00000013660	annotation not available	Eukaryotic translation initiation factor 2 alpha kinase 3.	0.806
ENSCAPP00000016515	NFE2L2	ENSCAPP00000016515	ENSCAPP00000001397	annotation not available	Nuclear factor, erythroid 2 like 2.	0.927
KEAP1	MAFK	ENSCAPP00000002999	ENSCAPP00000016705	Kelch like ECH associated protein 1.	MAF bZIP transcription factor K.	0.578
KEAP1	NFE2L2	ENSCAPP00000002999	ENSCAPP00000001397	Kelch like ECH associated protein 1.	Nuclear factor, erythroid 2 like 2.	0.999
KEAP1	PARK7	ENSCAPP00000002999	ENSCAPP00000000476	Kelch like ECH associated protein 1.	Parkinsonism associated deglycase.	0.550
KLHL17	NFE2L2	ENSCAPP00000003949	ENSCAPP00000001397	Kelch like family member 17.	Nuclear factor, erythroid 2 like 2.	0.969
KLHL18	NFE2L2	ENSCAPP00000008411	ENSCAPP00000001397	Kelch like family member 18.	Nuclear factor, erythroid 2 like 2.	0.930
MAFG	MAFK	ENSCAPP00000008868	ENSCAPP00000016705	MAF bZIP transcription factor G.	MAF bZIP transcription factor K.	0.788
MAFG	NFE2L2	ENSCAPP00000008868	ENSCAPP00000001397	MAF bZIP transcription factor G.	Nuclear factor, erythroid 2 like 2.	0.965
MAFK	KEAP1	ENSCAPP00000016705	ENSCAPP00000002999	MAF bZIP transcription factor K.	Kelch like ECH associated protein 1.	0.578
MAFK	MAFG	ENSCAPP00000016705	ENSCAPP00000008868	MAF bZIP transcription factor K.	MAF bZIP transcription factor G.	0.788
MAFK	NFE2L2	ENSCAPP00000016705	ENSCAPP00000001397	MAF bZIP transcription factor K.	Nuclear factor, erythroid 2 like 2.	0.939