Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
APIPAPAF1 interacting protein. (233 aa)    
Predicted Functional Partners:
ENOPH1
Enolase-phosphatase 1.
 
 0.993
ADI1
Acireductone dioxygenase 1.
 
 0.985
MRI1
Methylthioribose-1-phosphate isomerase 1.
 
 
 0.979
APAF1
Apoptotic peptidase activating factor 1.
    
 0.871
XYLB
Xylulokinase.
  
 
 0.816
LTO1
LTO1 maturation factor of ABCE1.
     
  0.798
NUDT18
Nudix hydrolase 18.
    
   0.776
EPHX2
Epoxide hydrolase 2.
    
 0.757
ENSCAPP00000018027
annotation not available
    
 0.738
CASP9
Caspase 9.
     
 0.733
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (10%) [HD]