STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JAK1Janus kinase 1. (1155 aa)    
Predicted Functional Partners:
STAT3
Signal transducer and activator of transcription 3.
   
 0.999
STAT1
Signal transducer and activator of transcription 1.
   
 0.999
IFNLR1
Interferon lambda receptor 1.
    
 0.997
IL2RB
Interleukin 2 receptor subunit beta.
    
 0.997
PTPN11
Protein tyrosine phosphatase non-receptor type 11.
    
 0.997
SOCS3
Suppressor of cytokine signaling 3.
    
 0.994
JAK3
Janus kinase 3.
   
 0.991
JAK2
Janus kinase 2.
   
 0.991
STAT6
Signal transducer and activator of transcription 6.
    
 0.990
IL7R
Interleukin 7 receptor.
   
 0.989
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.