STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JAK1Janus kinase 1. (1155 aa)    
Predicted Functional Partners:
IFNLR1
Interferon lambda receptor 1.
    
 0.993
STAT1
Signal transducer and activator of transcription 1.
   
 0.978
IL2RB
Interleukin 2 receptor subunit beta.
   
 0.976
STAT3
Signal transducer and activator of transcription 3.
   
 0.965
SOCS3
Suppressor of cytokine signaling 3.
   
 0.960
STAT6
Signal transducer and activator of transcription 6.
    
 0.953
STAT4
Signal transducer and activator of transcription 4.
   
 0.953
EPOR
Erythropoietin receptor.
    
 0.947
IL10RB
Interleukin 10 receptor subunit beta.
   
 0.946
JAK2
Janus kinase 2.
   
0.942
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.