Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPOPLSpeckle type BTB/POZ protein like. (390 aa)    
Predicted Functional Partners:
SPOP
Speckle type BTB/POZ protein.
   
  0.998
CUL3
Cullin 3.
   
 0.993
GLI3
GLI family zinc finger 3.
   
 0.989
GLI2
GLI family zinc finger 2.
   
 0.989
GLI1
GLI family zinc finger 1.
   
 0.970
SUFU
SUFU negative regulator of hedgehog signaling.
     
 0.951
RBX1
Ring-box 1.
    
 0.929
ENSCAPP00000016912
annotation not available
   
 
 0.921
SETD2
SET domain containing 2, histone lysine methyltransferase.
   
 
 0.917
NCOA3
Nuclear receptor coactivator 3.
    
 
 0.905
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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