ERBB3 protein (Cavia aperea) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

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[Homology]

Score

ERBB3

Erb-b2 receptor tyrosine kinase 3. (1259 aa)

Predicted Functional Partners:

NRG1

0.999

ERBB2

0.999

EGFR

0.998

ENSCAPP00000008635

0.998

ENSCAPP00000010381

0.997

GRB2

0.997

PIK3R1

0.997

EREG

0.997

SHC1

0.997

ENSCAPP00000003122

0.996

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGFR	ENSCAPP00000003122	ENSCAPP00000007783	ENSCAPP00000003122	Epidermal growth factor receptor.	annotation not available	0.996
EGFR	ENSCAPP00000008635	ENSCAPP00000007783	ENSCAPP00000008635	Epidermal growth factor receptor.	annotation not available	0.998
EGFR	ENSCAPP00000010381	ENSCAPP00000007783	ENSCAPP00000010381	Epidermal growth factor receptor.	annotation not available	0.963
EGFR	ERBB2	ENSCAPP00000007783	ENSCAPP00000010700	Epidermal growth factor receptor.	Erb-b2 receptor tyrosine kinase 2.	0.998
EGFR	ERBB3	ENSCAPP00000007783	ENSCAPP00000001439	Epidermal growth factor receptor.	Erb-b2 receptor tyrosine kinase 3.	0.998
EGFR	EREG	ENSCAPP00000007783	ENSCAPP00000017179	Epidermal growth factor receptor.	Epiregulin.	0.998
EGFR	GRB2	ENSCAPP00000007783	ENSCAPP00000011245	Epidermal growth factor receptor.	Growth factor receptor bound protein 2.	0.999
EGFR	NRG1	ENSCAPP00000007783	ENSCAPP00000007720	Epidermal growth factor receptor.	Neuregulin 1.	0.998
EGFR	PIK3R1	ENSCAPP00000007783	ENSCAPP00000016974	Epidermal growth factor receptor.	Phosphoinositide-3-kinase regulatory subunit 1.	0.998
EGFR	SHC1	ENSCAPP00000007783	ENSCAPP00000018127	Epidermal growth factor receptor.	SHC adaptor protein 1.	0.997
ENSCAPP00000003122	EGFR	ENSCAPP00000003122	ENSCAPP00000007783	annotation not available	Epidermal growth factor receptor.	0.996
ENSCAPP00000003122	ENSCAPP00000008635	ENSCAPP00000003122	ENSCAPP00000008635	annotation not available	annotation not available	0.443
ENSCAPP00000003122	ERBB2	ENSCAPP00000003122	ENSCAPP00000010700	annotation not available	Erb-b2 receptor tyrosine kinase 2.	0.996
ENSCAPP00000003122	ERBB3	ENSCAPP00000003122	ENSCAPP00000001439	annotation not available	Erb-b2 receptor tyrosine kinase 3.	0.996
ENSCAPP00000003122	EREG	ENSCAPP00000003122	ENSCAPP00000017179	annotation not available	Epiregulin.	0.433
ENSCAPP00000003122	GRB2	ENSCAPP00000003122	ENSCAPP00000011245	annotation not available	Growth factor receptor bound protein 2.	0.968
ENSCAPP00000003122	NRG1	ENSCAPP00000003122	ENSCAPP00000007720	annotation not available	Neuregulin 1.	0.443
ENSCAPP00000003122	PIK3R1	ENSCAPP00000003122	ENSCAPP00000016974	annotation not available	Phosphoinositide-3-kinase regulatory subunit 1.	0.999
ENSCAPP00000003122	SHC1	ENSCAPP00000003122	ENSCAPP00000018127	annotation not available	SHC adaptor protein 1.	0.777
ENSCAPP00000008635	EGFR	ENSCAPP00000008635	ENSCAPP00000007783	annotation not available	Epidermal growth factor receptor.	0.998