DENR protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

DENR

Density regulated re-initiation and release factor. (162 aa)

Predicted Functional Partners:

COPS4

0.910

ENSCAPP00000016629

0.903

ENSCAPP00000000576

0.900

ENSCAPP00000004781

0.900

COPS7A

0.896

ENSCAPP00000006028

0.891

ENSCAPP00000008538

0.881

ENSCAPP00000016878

0.878

RACK1

0.875

EIF3G

0.873

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COPS4	COPS7A	ENSCAPP00000000430	ENSCAPP00000012387	COP9 signalosome subunit 4.	COP9 signalosome subunit 7A.	0.999
COPS4	DENR	ENSCAPP00000000430	ENSCAPP00000001468	COP9 signalosome subunit 4.	Density regulated re-initiation and release factor.	0.910
COPS4	EIF3G	ENSCAPP00000000430	ENSCAPP00000000284	COP9 signalosome subunit 4.	Eukaryotic translation initiation factor 3 subunit G.	0.412
COPS4	ENSCAPP00000000576	ENSCAPP00000000430	ENSCAPP00000000576	COP9 signalosome subunit 4.	annotation not available	0.493
COPS4	ENSCAPP00000004781	ENSCAPP00000000430	ENSCAPP00000004781	COP9 signalosome subunit 4.	annotation not available	0.493
COPS7A	COPS4	ENSCAPP00000012387	ENSCAPP00000000430	COP9 signalosome subunit 7A.	COP9 signalosome subunit 4.	0.999
COPS7A	DENR	ENSCAPP00000012387	ENSCAPP00000001468	COP9 signalosome subunit 7A.	Density regulated re-initiation and release factor.	0.896
COPS7A	ENSCAPP00000000576	ENSCAPP00000012387	ENSCAPP00000000576	COP9 signalosome subunit 7A.	annotation not available	0.444
COPS7A	ENSCAPP00000004781	ENSCAPP00000012387	ENSCAPP00000004781	COP9 signalosome subunit 7A.	annotation not available	0.444
DENR	COPS4	ENSCAPP00000001468	ENSCAPP00000000430	Density regulated re-initiation and release factor.	COP9 signalosome subunit 4.	0.910
DENR	COPS7A	ENSCAPP00000001468	ENSCAPP00000012387	Density regulated re-initiation and release factor.	COP9 signalosome subunit 7A.	0.896
DENR	EIF3G	ENSCAPP00000001468	ENSCAPP00000000284	Density regulated re-initiation and release factor.	Eukaryotic translation initiation factor 3 subunit G.	0.873
DENR	ENSCAPP00000000576	ENSCAPP00000001468	ENSCAPP00000000576	Density regulated re-initiation and release factor.	annotation not available	0.900
DENR	ENSCAPP00000004781	ENSCAPP00000001468	ENSCAPP00000004781	Density regulated re-initiation and release factor.	annotation not available	0.900
DENR	ENSCAPP00000006028	ENSCAPP00000001468	ENSCAPP00000006028	Density regulated re-initiation and release factor.	annotation not available	0.891
DENR	ENSCAPP00000008538	ENSCAPP00000001468	ENSCAPP00000008538	Density regulated re-initiation and release factor.	annotation not available	0.881
DENR	ENSCAPP00000016629	ENSCAPP00000001468	ENSCAPP00000016629	Density regulated re-initiation and release factor.	annotation not available	0.903
DENR	ENSCAPP00000016878	ENSCAPP00000001468	ENSCAPP00000016878	Density regulated re-initiation and release factor.	annotation not available	0.878
DENR	RACK1	ENSCAPP00000001468	ENSCAPP00000015019	Density regulated re-initiation and release factor.	Receptor for activated C kinase 1.	0.875
EIF3G	COPS4	ENSCAPP00000000284	ENSCAPP00000000430	Eukaryotic translation initiation factor 3 subunit G.	COP9 signalosome subunit 4.	0.412