SFXN3 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

SFXN3

Sideroflexin 3. (283 aa)

Predicted Functional Partners:

HTT

0.788

ACAT1

0.762

ENSCAPP00000003131

0.660

RCN2

0.622

ESYT1

0.621

ENSCAPP00000005436

0.620

ENSCAPP00000006409

0.620

RAB25

0.612

SREK1IP1

0.611

ENSCAPP00000007730

0.569

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Export your current network:

... as a bitmap image:

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file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

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same PNG format, but at higher resolution

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAT1	SFXN3	ENSCAPP00000015745	ENSCAPP00000001498	acetyl-CoA acetyltransferase 1.	Sideroflexin 3.	0.762
ENSCAPP00000003131	ENSCAPP00000007730	ENSCAPP00000003131	ENSCAPP00000007730	annotation not available	annotation not available	0.741
ENSCAPP00000003131	SFXN3	ENSCAPP00000003131	ENSCAPP00000001498	annotation not available	Sideroflexin 3.	0.660
ENSCAPP00000005436	ENSCAPP00000006409	ENSCAPP00000005436	ENSCAPP00000006409	annotation not available	annotation not available	0.864
ENSCAPP00000005436	HTT	ENSCAPP00000005436	ENSCAPP00000018268	annotation not available	Huntingtin.	0.499
ENSCAPP00000005436	RAB25	ENSCAPP00000005436	ENSCAPP00000003390	annotation not available	RAB25, member RAS oncogene family.	0.581
ENSCAPP00000005436	SFXN3	ENSCAPP00000005436	ENSCAPP00000001498	annotation not available	Sideroflexin 3.	0.620
ENSCAPP00000006409	ENSCAPP00000005436	ENSCAPP00000006409	ENSCAPP00000005436	annotation not available	annotation not available	0.864
ENSCAPP00000006409	HTT	ENSCAPP00000006409	ENSCAPP00000018268	annotation not available	Huntingtin.	0.499
ENSCAPP00000006409	RAB25	ENSCAPP00000006409	ENSCAPP00000003390	annotation not available	RAB25, member RAS oncogene family.	0.581
ENSCAPP00000006409	SFXN3	ENSCAPP00000006409	ENSCAPP00000001498	annotation not available	Sideroflexin 3.	0.620
ENSCAPP00000007730	ENSCAPP00000003131	ENSCAPP00000007730	ENSCAPP00000003131	annotation not available	annotation not available	0.741
ENSCAPP00000007730	HTT	ENSCAPP00000007730	ENSCAPP00000018268	annotation not available	Huntingtin.	0.788
ENSCAPP00000007730	SFXN3	ENSCAPP00000007730	ENSCAPP00000001498	annotation not available	Sideroflexin 3.	0.569
ESYT1	SFXN3	ENSCAPP00000000979	ENSCAPP00000001498	Extended synaptotagmin 1.	Sideroflexin 3.	0.621
HTT	ENSCAPP00000005436	ENSCAPP00000018268	ENSCAPP00000005436	Huntingtin.	annotation not available	0.499
HTT	ENSCAPP00000006409	ENSCAPP00000018268	ENSCAPP00000006409	Huntingtin.	annotation not available	0.499
HTT	ENSCAPP00000007730	ENSCAPP00000018268	ENSCAPP00000007730	Huntingtin.	annotation not available	0.788
HTT	SFXN3	ENSCAPP00000018268	ENSCAPP00000001498	Huntingtin.	Sideroflexin 3.	0.788
RAB25	ENSCAPP00000005436	ENSCAPP00000003390	ENSCAPP00000005436	RAB25, member RAS oncogene family.	annotation not available	0.581