STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AURKCAurora kinase C. (290 aa)    
Predicted Functional Partners:
INCENP
Inner centromere protein.
   
 0.996
CDCA8
Cell division cycle associated 8.
   
 0.990
CDK1
Cyclin dependent kinase 1.
   
 0.955
CENPA
Centromere protein A.
   
 
 0.943
AURKB
Aurora kinase B.
  
 
0.937
CDC20
Cell division cycle 20.
   
 0.935
PLK1
Polo like kinase 1.
   
0.925
BIRC6
Baculoviral IAP repeat containing 6.
   
 0.916
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.914
UBE2C
Ubiquitin conjugating enzyme E2 C.
   
 0.903
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.