Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AURKCAurora kinase C. (290 aa)    
Predicted Functional Partners:
INCENP
Inner centromere protein.
   
 0.999
CDCA8
Cell division cycle associated 8.
   
 0.997
AURKB
Aurora kinase B.
   
 0.986
CENPA
Centromere protein A.
   
 
 0.981
NDC80
NDC80 kinetochore complex component.
   
 
 0.965
ENSCAPP00000005423
annotation not available
   
  0.961
ENSCAPP00000013539
annotation not available
   
  0.961
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.959
CDC20
Cell division cycle 20.
   
 0.957
CDK1
Cyclin dependent kinase 1.
   
 0.954
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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