STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LZTS2Leucine zipper tumor suppressor 2. (668 aa)    
Predicted Functional Partners:
LZTS1
Leucine zipper tumor suppressor 1.
    
   0.932
CTNNB1
Catenin beta 1.
    
 0.930
SHANK3
SH3 and multiple ankyrin repeat domains 3.
    
 0.890
SHANK1
SH3 and multiple ankyrin repeat domains 1.
    
 0.886
SHANK2
SH3 and multiple ankyrin repeat domains 2.
     
 0.874
SIPA1L1
Signal induced proliferation associated 1 like 1.
    
 
 0.862
DYRK1B
Dual specificity tyrosine phosphorylation regulated kinase 1B.
    
 
 0.802
DYRK1A
Dual specificity tyrosine phosphorylation regulated kinase 1A.
    
   0.800
JUP
Junction plakoglobin.
    
 0.799
AFDN
Afadin, adherens junction formation factor.
    
 
 0.710
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.