Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TBC1D1TBC1 domain family member 1. (1164 aa)    
Predicted Functional Partners:
RAB8A
RAB8A, member RAS oncogene family.
    
 0.961
RAB14
RAB14, member RAS oncogene family.
    
 0.952
RAB10
RAB10, member RAS oncogene family.
    
 0.948
RAB2A
RAB2A, member RAS oncogene family.
    
 0.946
PRKAA1
Protein kinase AMP-activated catalytic subunit alpha 1.
    
 0.938
RAB8B
RAB8B, member RAS oncogene family.
    
 0.936
ENSCAPP00000011372
annotation not available
    
   0.936
PRKAA2
Protein kinase AMP-activated catalytic subunit alpha 2.
    
 0.935
PRKAG3
Protein kinase AMP-activated non-catalytic subunit gamma 3.
    
 0.927
PRKAG2
Protein kinase AMP-activated non-catalytic subunit gamma 2.
    
 0.924
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (18%) [HD]