OSBPL5 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

OSBPL5

Oxysterol binding protein like 5. (871 aa)

Predicted Functional Partners:

OSBPL8

0.958

NPC1

0.951

NPC1L1

0.888

ENSCAPP00000018460

0.841

SLC22A18

0.818

VAPB

0.672

VAPA

0.617

GALE

0.591

UXS1

0.587

GM2A

0.571

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCAPP00000018460	OSBPL5	ENSCAPP00000018460	ENSCAPP00000001649	annotation not available	Oxysterol binding protein like 5.	0.841
ENSCAPP00000018460	OSBPL8	ENSCAPP00000018460	ENSCAPP00000014238	annotation not available	Oxysterol binding protein like 8.	0.959
GALE	OSBPL5	ENSCAPP00000005406	ENSCAPP00000001649	UDP-galactose-4-epimerase.	Oxysterol binding protein like 5.	0.591
GALE	OSBPL8	ENSCAPP00000005406	ENSCAPP00000014238	UDP-galactose-4-epimerase.	Oxysterol binding protein like 8.	0.591
GALE	UXS1	ENSCAPP00000005406	ENSCAPP00000004657	UDP-galactose-4-epimerase.	UDP-glucuronate decarboxylase 1.	0.899
GM2A	OSBPL5	ENSCAPP00000000198	ENSCAPP00000001649	GM2 ganglioside activator.	Oxysterol binding protein like 5.	0.571
GM2A	OSBPL8	ENSCAPP00000000198	ENSCAPP00000014238	GM2 ganglioside activator.	Oxysterol binding protein like 8.	0.847
NPC1	OSBPL5	ENSCAPP00000015113	ENSCAPP00000001649	NPC intracellular cholesterol transporter 1.	Oxysterol binding protein like 5.	0.951
NPC1	OSBPL8	ENSCAPP00000015113	ENSCAPP00000014238	NPC intracellular cholesterol transporter 1.	Oxysterol binding protein like 8.	0.799
NPC1L1	OSBPL5	ENSCAPP00000011019	ENSCAPP00000001649	NPC1 like intracellular cholesterol transporter 1.	Oxysterol binding protein like 5.	0.888
NPC1L1	OSBPL8	ENSCAPP00000011019	ENSCAPP00000014238	NPC1 like intracellular cholesterol transporter 1.	Oxysterol binding protein like 8.	0.798
OSBPL5	ENSCAPP00000018460	ENSCAPP00000001649	ENSCAPP00000018460	Oxysterol binding protein like 5.	annotation not available	0.841
OSBPL5	GALE	ENSCAPP00000001649	ENSCAPP00000005406	Oxysterol binding protein like 5.	UDP-galactose-4-epimerase.	0.591
OSBPL5	GM2A	ENSCAPP00000001649	ENSCAPP00000000198	Oxysterol binding protein like 5.	GM2 ganglioside activator.	0.571
OSBPL5	NPC1	ENSCAPP00000001649	ENSCAPP00000015113	Oxysterol binding protein like 5.	NPC intracellular cholesterol transporter 1.	0.951
OSBPL5	NPC1L1	ENSCAPP00000001649	ENSCAPP00000011019	Oxysterol binding protein like 5.	NPC1 like intracellular cholesterol transporter 1.	0.888
OSBPL5	OSBPL8	ENSCAPP00000001649	ENSCAPP00000014238	Oxysterol binding protein like 5.	Oxysterol binding protein like 8.	0.958
OSBPL5	SLC22A18	ENSCAPP00000001649	ENSCAPP00000008468	Oxysterol binding protein like 5.	Solute carrier family 22 member 18.	0.818
OSBPL5	UXS1	ENSCAPP00000001649	ENSCAPP00000004657	Oxysterol binding protein like 5.	UDP-glucuronate decarboxylase 1.	0.587
OSBPL5	VAPA	ENSCAPP00000001649	ENSCAPP00000005991	Oxysterol binding protein like 5.	VAMP associated protein A.	0.617