Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTPRMProtein tyrosine phosphatase receptor type M. (1445 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
    
  0.937
CTNND1
Catenin delta 1.
    
 0.933
PTPN6
Protein tyrosine phosphatase non-receptor type 6.
   
 0.926
PTPRA
Protein tyrosine phosphatase receptor type A.
    
 0.841
CDH1
Cadherin 1.
    
   0.837
PTPRQ
Protein tyrosine phosphatase receptor type Q.
    
 0.833
PTPN3
Protein tyrosine phosphatase non-receptor type 3.
    
 
 0.831
PTPRK
Protein tyrosine phosphatase receptor type K.
    
 0.812
ARVCF
ARVCF delta catenin family member.
    
 0.796
RACK1
Receptor for activated C kinase 1.
    
   0.785
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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