STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPRMProtein tyrosine phosphatase receptor type M. (1445 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
    
 0.938
CTNND1
Catenin delta 1.
    
 0.924
PTK7
Protein tyrosine kinase 7 (inactive).
    
 0.715
LRIT3
Leucine rich repeat, Ig-like and transmembrane domains 3.
    
  0.707
LRIT1
Leucine rich repeat, Ig-like and transmembrane domains 1.
    
  0.707
JUP
Junction plakoglobin.
    
 0.703
PTPN6
Protein tyrosine phosphatase non-receptor type 6.
   
0.669
ROR2
Receptor tyrosine kinase like orphan receptor 2.
    
  0.662
ROR1
Receptor tyrosine kinase like orphan receptor 1.
    
  0.662
GRB2
Growth factor receptor bound protein 2.
   
 0.655
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.