Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARFGEF3ARFGEF family member 3. (2089 aa)    
Predicted Functional Partners:
PHB2
Prohibitin 2.
    
 
 0.979
KCNH7
Potassium voltage-gated channel subfamily H member 7.
   
  
 0.749
CCDC167
Coiled-coil domain containing 167.
      
 0.738
ORC5
Origin recognition complex subunit 5.
      
 0.688
PKIA
cAMP-dependent protein kinase inhibitor alpha.
      
 0.627
LRRTM4
Leucine rich repeat transmembrane neuronal 4.
      
 0.614
SLC12A1
Solute carrier family 12 member 1.
      
 0.603
DRG2
Developmentally regulated GTP binding protein 2.
      
 0.574
PHB
Prohibitin.
    
 
 0.572
PHACTR2
Phosphatase and actin regulator 2.
      
 0.569
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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