TWF2 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TWF2

Twinfilin actin binding protein 2. (348 aa)

Predicted Functional Partners:

CAPZB

0.968

CAPZA1

0.947

WDR82

0.894

CAP2

0.815

ENSCAPP00000004593

0.793

CAPZA3

0.753

ENSCAPP00000016412

0.753

ESPNL

0.752

ENSCAPP00000010888

0.752

WHRN

0.723

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAP2	CAPZB	ENSCAPP00000009860	ENSCAPP00000001527	Cyclase associated actin cytoskeleton regulatory protein 2.	Capping actin protein of muscle Z-line subunit beta.	0.609
CAP2	ENSCAPP00000004593	ENSCAPP00000009860	ENSCAPP00000004593	Cyclase associated actin cytoskeleton regulatory protein 2.	annotation not available	0.768
CAP2	TWF2	ENSCAPP00000009860	ENSCAPP00000001754	Cyclase associated actin cytoskeleton regulatory protein 2.	Twinfilin actin binding protein 2.	0.815
CAPZA1	CAPZA3	ENSCAPP00000017322	ENSCAPP00000013143	Capping actin protein of muscle Z-line subunit alpha 1.	Capping actin protein of muscle Z-line subunit alpha 3.	0.964
CAPZA1	CAPZB	ENSCAPP00000017322	ENSCAPP00000001527	Capping actin protein of muscle Z-line subunit alpha 1.	Capping actin protein of muscle Z-line subunit beta.	0.998
CAPZA1	ENSCAPP00000010888	ENSCAPP00000017322	ENSCAPP00000010888	Capping actin protein of muscle Z-line subunit alpha 1.	annotation not available	0.520
CAPZA1	ENSCAPP00000016412	ENSCAPP00000017322	ENSCAPP00000016412	Capping actin protein of muscle Z-line subunit alpha 1.	annotation not available	0.964
CAPZA1	ESPNL	ENSCAPP00000017322	ENSCAPP00000010844	Capping actin protein of muscle Z-line subunit alpha 1.	Espin like.	0.529
CAPZA1	TWF2	ENSCAPP00000017322	ENSCAPP00000001754	Capping actin protein of muscle Z-line subunit alpha 1.	Twinfilin actin binding protein 2.	0.947
CAPZA3	CAPZA1	ENSCAPP00000013143	ENSCAPP00000017322	Capping actin protein of muscle Z-line subunit alpha 3.	Capping actin protein of muscle Z-line subunit alpha 1.	0.964
CAPZA3	CAPZB	ENSCAPP00000013143	ENSCAPP00000001527	Capping actin protein of muscle Z-line subunit alpha 3.	Capping actin protein of muscle Z-line subunit beta.	0.984
CAPZA3	ENSCAPP00000010888	ENSCAPP00000013143	ENSCAPP00000010888	Capping actin protein of muscle Z-line subunit alpha 3.	annotation not available	0.441
CAPZA3	ESPNL	ENSCAPP00000013143	ENSCAPP00000010844	Capping actin protein of muscle Z-line subunit alpha 3.	Espin like.	0.441
CAPZA3	TWF2	ENSCAPP00000013143	ENSCAPP00000001754	Capping actin protein of muscle Z-line subunit alpha 3.	Twinfilin actin binding protein 2.	0.753
CAPZB	CAP2	ENSCAPP00000001527	ENSCAPP00000009860	Capping actin protein of muscle Z-line subunit beta.	Cyclase associated actin cytoskeleton regulatory protein 2.	0.609
CAPZB	CAPZA1	ENSCAPP00000001527	ENSCAPP00000017322	Capping actin protein of muscle Z-line subunit beta.	Capping actin protein of muscle Z-line subunit alpha 1.	0.998
CAPZB	CAPZA3	ENSCAPP00000001527	ENSCAPP00000013143	Capping actin protein of muscle Z-line subunit beta.	Capping actin protein of muscle Z-line subunit alpha 3.	0.984
CAPZB	ENSCAPP00000004593	ENSCAPP00000001527	ENSCAPP00000004593	Capping actin protein of muscle Z-line subunit beta.	annotation not available	0.644
CAPZB	ENSCAPP00000010888	ENSCAPP00000001527	ENSCAPP00000010888	Capping actin protein of muscle Z-line subunit beta.	annotation not available	0.599
CAPZB	ENSCAPP00000016412	ENSCAPP00000001527	ENSCAPP00000016412	Capping actin protein of muscle Z-line subunit beta.	annotation not available	0.984