STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PYGO1Pygopus family PHD finger 1. (419 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
    
 0.967
BCL9
BCL9 transcription coactivator.
    
 0.942
JUP
Junction plakoglobin.
    
 0.940
LEF1
Lymphoid enhancer binding factor 1.
    
 0.745
LDB2
LIM domain binding 2.
    
 0.705
LDB1
LIM domain binding 1.
    
 0.705
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
    
 0.703
TCF7L1
Transcription factor 7 like 1.
    
 0.669
ENSCAPP00000017363
annotation not available
    
 0.669
UNC79
Unc-79 homolog, NALCN channel complex subunit.
    
 0.649
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.