STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1. (2873 aa)    
Predicted Functional Partners:
VANGL2
VANGL planar cell polarity protein 2.
    
 0.746
VANGL1
VANGL planar cell polarity protein 1.
    
 0.744
FZD6
Frizzled class receptor 6.
    
 0.697
FZD3
Frizzled class receptor 3.
    
 0.668
PRICKLE1
Prickle planar cell polarity protein 1.
   
 0.568
PRICKLE2
Prickle planar cell polarity protein 2.
   
 0.560
ENSCAPP00000009531
annotation not available
      
 0.560
BRD1
Bromodomain containing 1.
      
 0.556
ENSCAPP00000016139
annotation not available
      
 0.547
ZDHHC8
Zinc finger DHHC-type containing 8.
      
 0.535
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (32%) [HD]