Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SGIP1SH3GL interacting endocytic adaptor 1. (826 aa)    
Predicted Functional Partners:
EPS15
Epidermal growth factor receptor pathway substrate 15.
    
 0.998
EPS15L1
Epidermal growth factor receptor pathway substrate 15 like 1.
    
 0.993
AP2B1
Adaptor related protein complex 2 subunit beta 1.
    
 0.984
AP2S1
Adaptor related protein complex 2 subunit sigma 1.
    
 0.980
ENSCAPP00000013876
annotation not available
   
 0.979
AP2A1
Adaptor related protein complex 2 subunit alpha 1.
    
 0.976
ITSN2
Intersectin 2.
    
 0.966
ITSN1
Intersectin 1.
    
 0.963
ENSCAPP00000013032
annotation not available
    
 0.963
AP2A2
Adaptor related protein complex 2 subunit alpha 2.
    
 0.960
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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