STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (294 aa)    
Predicted Functional Partners:
ERCC4
ERCC excision repair 4, endonuclease catalytic subunit.
   
 0.999
ENSCAPP00000010526
annotation not available
    
 0.997
MSH2
mutS homolog 2.
    
 0.990
FANCL
FA complementation group L.
    
 0.981
MSH6
mutS homolog 6.
    
 0.976
RAD23A
RAD23 homolog A, nucleotide excision repair protein.
    
 0.971
MUS81
MUS81 structure-specific endonuclease subunit.
   
 0.969
ENSCAPP00000013410
annotation not available
    
 0.967
ENSCAPP00000001141
annotation not available
    
 0.965
MLH1
mutL homolog 1.
    
 0.965
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.