STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HGSHepatocyte growth factor-regulated tyrosine kinase substrate. (799 aa)    
Predicted Functional Partners:
STAM
Signal transducing adaptor molecule.
   
 0.999
TSG101
Tumor susceptibility 101.
    
 0.998
STAM2
Signal transducing adaptor molecule 2.
   
 0.998
EPS15
Epidermal growth factor receptor pathway substrate 15.
   
 0.997
VPS28
VPS28 subunit of ESCRT-I.
    
 0.996
VPS37A
VPS37A subunit of ESCRT-I.
    
 0.993
UBAP1
Ubiquitin associated protein 1.
   
 0.993
CLTC
Clathrin heavy chain.
    
 0.986
EGFR
Epidermal growth factor receptor.
    
 0.982
MVB12A
Multivesicular body subunit 12A.
    
 0.981
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.