Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IFNLR1Interferon lambda receptor 1. (509 aa)    
Predicted Functional Partners:
JAK1
Janus kinase 1.
    
 0.997
TYK2
Tyrosine kinase 2.
    
 0.988
ENSCAPP00000004275
annotation not available
    
 0.984
ENSCAPP00000006472
annotation not available
    
 0.984
IL10RB
Interleukin 10 receptor subunit beta.
    
 0.977
TP53BP2
Tumor protein p53 binding protein 2.
    
 0.977
STAT1
Signal transducer and activator of transcription 1.
    
 0.964
ENSCAPP00000009742
annotation not available
    
 0.952
STAT4
Signal transducer and activator of transcription 4.
    
 0.900
JAK3
Janus kinase 3.
    
 0.893
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: medium (70%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.