Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMUB2Transmembrane and ubiquitin like domain containing 2. (309 aa)    
Predicted Functional Partners:
TMUB1
Transmembrane and ubiquitin like domain containing 1.
    
   0.955
ERLIN2
ER lipid raft associated 2.
    
 
 0.952
TMEM259
Transmembrane protein 259.
    
 
 0.874
RNF185
Ring finger protein 185.
    
 
 0.693
RNF5
Ring finger protein 5.
    
 
 0.693
RNF170
Ring finger protein 170.
    
 
 0.691
THSD7A
Thrombospondin type 1 domain containing 7A.
    
   0.622
HERPUD2
HERPUD family member 2.
      
 0.588
GEMIN4
Gem nuclear organelle associated protein 4.
      
 0.582
ENSCAPP00000002046
annotation not available
      
 0.571
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (24%) [HD]