Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ALOX12Arachidonate 12-lipoxygenase, 12S type. (496 aa)    
Predicted Functional Partners:
PTGS2
Prostaglandin-endoperoxide synthase 2.
    
 0.939
PTGS1
Prostaglandin-endoperoxide synthase 1.
    
 0.939
CYP2U1
Cytochrome P450 family 2 subfamily U member 1.
    
  0.938
GPX4
Glutathione peroxidase 4.
     
 0.934
ALOX12B
Arachidonate 12-lipoxygenase, 12R type.
     
  0.934
ALOX15B
Arachidonate 15-lipoxygenase type B.
     
  0.934
ENSCAPP00000000079
annotation not available
    
 0.924
PLA2G12B
Phospholipase A2 group XIIB.
    
 0.923
PLA2G6
Phospholipase A2 group VI.
   
 
 0.919
CYP2E1
Cytochrome P450 family 2 subfamily E member 1.
    
  0.917
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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