Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KLHL20Kelch like family member 20. (593 aa)    
Predicted Functional Partners:
CUL3
Cullin 3.
    
 0.990
DAPK1
Death associated protein kinase 1.
    
 
 0.967
ENSCAPP00000001227
annotation not available
    
 
 0.931
KLHL12
Kelch like family member 12.
    
  0.917
KLHL26
Kelch like family member 26.
    
  0.895
SQSTM1
Sequestosome 1.
    
 0.892
NFE2L2
Nuclear factor, erythroid 2 like 2.
    
 0.842
NFE2L1
Nuclear factor, erythroid 2 like 1.
    
 0.842
RBX1
Ring-box 1.
    
 0.829
ENSCAPP00000001389
annotation not available
    
  0.815
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (18%) [HD]