ERBIN protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ERBIN

Erbb2 interacting protein. (1289 aa)

Predicted Functional Partners:

ERBB2

0.990

PKP4

0.969

NOD2

0.954

ENSCAPP00000002730

0.948

SMAD2

0.948

ENSCAPP00000000802

0.903

PPP1CA

0.903

PTRH2

0.886

ENSCAPP00000005516

0.876

ENSCAPP00000016001

0.833

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCAPP00000000802	ERBIN	ENSCAPP00000000802	ENSCAPP00000002226	annotation not available	Erbb2 interacting protein.	0.903
ENSCAPP00000000802	PPP1CA	ENSCAPP00000000802	ENSCAPP00000017677	annotation not available	Protein phosphatase 1 catalytic subunit alpha.	0.991
ENSCAPP00000002730	ERBIN	ENSCAPP00000002730	ENSCAPP00000002226	annotation not available	Erbb2 interacting protein.	0.948
ENSCAPP00000002730	SMAD2	ENSCAPP00000002730	ENSCAPP00000014295	annotation not available	SMAD family member 2.	0.999
ENSCAPP00000005516	ERBB2	ENSCAPP00000005516	ENSCAPP00000010700	annotation not available	Erb-b2 receptor tyrosine kinase 2.	0.607
ENSCAPP00000005516	ERBIN	ENSCAPP00000005516	ENSCAPP00000002226	annotation not available	Erbb2 interacting protein.	0.876
ENSCAPP00000016001	ERBIN	ENSCAPP00000016001	ENSCAPP00000002226	annotation not available	Erbb2 interacting protein.	0.833
ERBB2	ENSCAPP00000005516	ENSCAPP00000010700	ENSCAPP00000005516	Erb-b2 receptor tyrosine kinase 2.	annotation not available	0.607
ERBB2	ERBIN	ENSCAPP00000010700	ENSCAPP00000002226	Erb-b2 receptor tyrosine kinase 2.	Erbb2 interacting protein.	0.990
ERBB2	PKP4	ENSCAPP00000010700	ENSCAPP00000016299	Erb-b2 receptor tyrosine kinase 2.	Plakophilin 4.	0.607
ERBIN	ENSCAPP00000000802	ENSCAPP00000002226	ENSCAPP00000000802	Erbb2 interacting protein.	annotation not available	0.903
ERBIN	ENSCAPP00000002730	ENSCAPP00000002226	ENSCAPP00000002730	Erbb2 interacting protein.	annotation not available	0.948
ERBIN	ENSCAPP00000005516	ENSCAPP00000002226	ENSCAPP00000005516	Erbb2 interacting protein.	annotation not available	0.876
ERBIN	ENSCAPP00000016001	ENSCAPP00000002226	ENSCAPP00000016001	Erbb2 interacting protein.	annotation not available	0.833
ERBIN	ERBB2	ENSCAPP00000002226	ENSCAPP00000010700	Erbb2 interacting protein.	Erb-b2 receptor tyrosine kinase 2.	0.990
ERBIN	NOD2	ENSCAPP00000002226	ENSCAPP00000017799	Erbb2 interacting protein.	Nucleotide binding oligomerization domain containing 2.	0.954
ERBIN	PKP4	ENSCAPP00000002226	ENSCAPP00000016299	Erbb2 interacting protein.	Plakophilin 4.	0.969
ERBIN	PPP1CA	ENSCAPP00000002226	ENSCAPP00000017677	Erbb2 interacting protein.	Protein phosphatase 1 catalytic subunit alpha.	0.903
ERBIN	PTRH2	ENSCAPP00000002226	ENSCAPP00000001975	Erbb2 interacting protein.	peptidyl-tRNA hydrolase 2.	0.886
ERBIN	SMAD2	ENSCAPP00000002226	ENSCAPP00000014295	Erbb2 interacting protein.	SMAD family member 2.	0.948