UCHL1 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

UCHL1

Ubiquitin C-terminal hydrolase L1. (142 aa)

Predicted Functional Partners:

TP53

0.951

EGFR

0.939

UBA52

0.910

ENSCAPP00000010366

0.910

ENSCAPP00000000492

0.902

ENSCAPP00000004155

0.902

ENSCAPP00000009519

0.902

ENSCAPP00000014462

0.902

ENSCAPP00000001899

0.901

ENSCAPP00000012837

0.901

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGFR	ENSCAPP00000000492	ENSCAPP00000007783	ENSCAPP00000000492	Epidermal growth factor receptor.	annotation not available	0.718
EGFR	ENSCAPP00000004155	ENSCAPP00000007783	ENSCAPP00000004155	Epidermal growth factor receptor.	annotation not available	0.718
EGFR	ENSCAPP00000010366	ENSCAPP00000007783	ENSCAPP00000010366	Epidermal growth factor receptor.	annotation not available	0.430
EGFR	ENSCAPP00000014462	ENSCAPP00000007783	ENSCAPP00000014462	Epidermal growth factor receptor.	annotation not available	0.718
EGFR	TP53	ENSCAPP00000007783	ENSCAPP00000017521	Epidermal growth factor receptor.	Tumor protein p53.	0.900
EGFR	UBA52	ENSCAPP00000007783	ENSCAPP00000005037	Epidermal growth factor receptor.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.430
EGFR	UCHL1	ENSCAPP00000007783	ENSCAPP00000002243	Epidermal growth factor receptor.	Ubiquitin C-terminal hydrolase L1.	0.939
ENSCAPP00000000492	EGFR	ENSCAPP00000000492	ENSCAPP00000007783	annotation not available	Epidermal growth factor receptor.	0.718
ENSCAPP00000000492	ENSCAPP00000001899	ENSCAPP00000000492	ENSCAPP00000001899	annotation not available	annotation not available	0.916
ENSCAPP00000000492	ENSCAPP00000009519	ENSCAPP00000000492	ENSCAPP00000009519	annotation not available	annotation not available	0.941
ENSCAPP00000000492	ENSCAPP00000010366	ENSCAPP00000000492	ENSCAPP00000010366	annotation not available	annotation not available	0.991
ENSCAPP00000000492	ENSCAPP00000012837	ENSCAPP00000000492	ENSCAPP00000012837	annotation not available	annotation not available	0.916
ENSCAPP00000000492	TP53	ENSCAPP00000000492	ENSCAPP00000017521	annotation not available	Tumor protein p53.	0.945
ENSCAPP00000000492	UBA52	ENSCAPP00000000492	ENSCAPP00000005037	annotation not available	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.991
ENSCAPP00000000492	UCHL1	ENSCAPP00000000492	ENSCAPP00000002243	annotation not available	Ubiquitin C-terminal hydrolase L1.	0.902
ENSCAPP00000001899	ENSCAPP00000000492	ENSCAPP00000001899	ENSCAPP00000000492	annotation not available	annotation not available	0.916
ENSCAPP00000001899	ENSCAPP00000004155	ENSCAPP00000001899	ENSCAPP00000004155	annotation not available	annotation not available	0.916
ENSCAPP00000001899	ENSCAPP00000009519	ENSCAPP00000001899	ENSCAPP00000009519	annotation not available	annotation not available	0.899
ENSCAPP00000001899	ENSCAPP00000010366	ENSCAPP00000001899	ENSCAPP00000010366	annotation not available	annotation not available	0.961
ENSCAPP00000001899	ENSCAPP00000012837	ENSCAPP00000001899	ENSCAPP00000012837	annotation not available	annotation not available	0.709