Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GSK3AGlycogen synthase kinase 3 alpha. (472 aa)    
Predicted Functional Partners:
GSK3B
Glycogen synthase kinase 3 beta.
   
  0.999
AKT1
AKT serine/threonine kinase 1.
    
 0.998
CTNNB1
Catenin beta 1.
    
 0.998
AXIN1
Axin 1.
   
 0.998
AXIN2
Axin 2.
    
 0.997
ENSCAPP00000012429
annotation not available
    
 0.996
APC
APC regulator of WNT signaling pathway.
    
 0.993
PPP3CC
Protein phosphatase 3 catalytic subunit gamma.
    
 0.988
MYC
MYC proto-oncogene, bHLH transcription factor.
    
 0.985
APC2
APC regulator of WNT signaling pathway 2.
    
 0.984
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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