Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNF145Ring finger protein 145. (534 aa)    
Predicted Functional Partners:
MARCHF6
Membrane associated ring-CH-type finger 6.
    
 0.881
NPEPL1
Aminopeptidase like 1.
      
 0.842
VCP
Valosin containing protein.
    
 0.829
UBE2G2
Ubiquitin conjugating enzyme E2 G2.
    
 0.826
UFD1
Ubiquitin recognition factor in ER associated degradation 1.
   
 0.800
DERL1
Derlin 1.
    
 0.785
ENSCAPP00000005200
annotation not available
   
 
 0.776
ERLEC1
Endoplasmic reticulum lectin 1.
    
 0.764
OS9
OS9 endoplasmic reticulum lectin.
    
 0.764
DERL2
Derlin 2.
    
 0.752
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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