STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIK3AP1Phosphoinositide-3-kinase adaptor protein 1. (621 aa)    
Predicted Functional Partners:
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
     
 0.920
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta.
     
 0.907
SYK
Spleen associated tyrosine kinase.
    
 0.842
ENSCAPP00000003122
annotation not available
     
 0.807
PIK3CA
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
     
 0.807
ENSCAPP00000015345
annotation not available
     
 0.807
ZAP70
Zeta chain of T cell receptor associated protein kinase 70.
    
 0.738
GRB2
Growth factor receptor bound protein 2.
    
  0.677
NCK2
NCK adaptor protein 2.
    
   0.529
DAPP1
Dual adaptor of phosphotyrosine and 3-phosphoinositides 1.
     
 0.495
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.