Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1189 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.999
EGFR
Epidermal growth factor receptor.
    
 0.998
PTPN11
Protein tyrosine phosphatase non-receptor type 11.
    
 0.998
SHC1
SHC adaptor protein 1.
    
 0.998
ENSCAPP00000013002
annotation not available
    
 0.996
SHC3
SHC adaptor protein 3.
    
 0.994
FGFR1
Fibroblast growth factor receptor 1.
    
 0.986
EPS8
Epidermal growth factor receptor pathway substrate 8.
    
 
 0.986
NCK1
NCK adaptor protein 1.
    
 0.985
FRS2
Fibroblast growth factor receptor substrate 2.
   
 0.984
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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