Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GREM1Gremlin 1, DAN family BMP antagonist. (184 aa)    
Predicted Functional Partners:
BMP4
Bone morphogenetic protein 4.
     
 0.951
BMP6
Bone morphogenetic protein 6.
     
 0.899
GREM2
Gremlin 2, DAN family BMP antagonist.
     
  0.896
BMP5
Bone morphogenetic protein 5.
     
 0.891
GDF5
Growth differentiation factor 5.
     
 0.873
ENSCAPP00000008999
annotation not available
     
 0.865
ENSCAPP00000006608
annotation not available
     
  0.850
ENSCAPP00000001654
annotation not available
     
  0.840
GLI3
GLI family zinc finger 3.
    
 
 0.546
FMN1
Formin 1.
      
 0.537
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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