Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DENND2ADENN domain containing 2A. (677 aa)    
Predicted Functional Partners:
RHOBTB3
Rho related BTB domain containing 3.
      
 0.773
RAB9A
RAB9A, member RAS oncogene family.
     
 0.721
AVL9
AVL9 cell migration associated.
      
 0.665
GALNT6
Polypeptide N-acetylgalactosaminyltransferase 6.
      
 0.658
RAB35
RAB35, member RAS oncogene family.
    
 0.651
IFT27
Intraflagellar transport 27.
    
 0.651
ADAMTSL1
ADAMTS like 1.
      
 0.644
DENND3
DENN domain containing 3.
    
   0.583
ENSCAPP00000017549
annotation not available
      
 0.581
ITSN2
Intersectin 2.
    
 
 0.579
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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