close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNK4Potassium two pore domain channel subfamily K member 4. (382 aa)    
Predicted Functional Partners:
KCNJ13
Potassium inwardly rectifying channel subfamily J member 13.
     
 0.639
KCNE3
Potassium voltage-gated channel subfamily E regulatory subunit 3.
     
 0.620
KCNK1
Potassium two pore domain channel subfamily K member 1.
     
0.614
KCNK2
Potassium two pore domain channel subfamily K member 2.
     
0.586
ENSCAPP00000015664
annotation not available
     
0.581
SGSM2
Small G protein signaling modulator 2.
      
 0.557
KCNK7
Potassium two pore domain channel subfamily K member 7.
     
 0.550
KCNK5
Potassium two pore domain channel subfamily K member 5.
     
0.531
GPR137
G protein-coupled receptor 137.
      
 0.528
MEX3C
Mex-3 RNA binding family member C.
      
 0.527
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (22%) [HD]