STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPARAPeroxisome proliferator activated receptor alpha. (467 aa)    
Predicted Functional Partners:
PPARGC1A
PPARG coactivator 1 alpha.
    
 0.998
RXRA
Retinoid X receptor alpha.
   
 0.998
RXRG
Retinoid X receptor gamma.
   
 0.994
SIRT1
Sirtuin 1.
    
 0.987
RXRB
Retinoid X receptor beta.
    
 0.987
NCOR2
Nuclear receptor corepressor 2.
    
 0.980
EP300
E1A binding protein p300.
    
 0.980
MED1
Mediator complex subunit 1.
    
 0.979
NCOA1
Nuclear receptor coactivator 1.
    
 0.979
NR1H3
Nuclear receptor subfamily 1 group H member 3.
    
 0.973
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.