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Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RUNX2RUNX family transcription factor 2. (490 aa)    
Predicted Functional Partners:
MYSM1
Myb like, SWIRM and MPN domains 1.
    
  0.981
CBFB
Core-binding factor subunit beta.
    
 0.966
FOS
Fos proto-oncogene, AP-1 transcription factor subunit.
    
 0.889
ETS1
ETS proto-oncogene 1, transcription factor.
   
 0.862
ENSCAPP00000002314
annotation not available
    
 0.837
ENSCAPP00000002730
annotation not available
   
 0.815
HDAC1
Histone deacetylase 1.
    
 0.811
HDAC5
Histone deacetylase 5.
    
 0.811
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha.
     
 0.808
PRKACB
Protein kinase cAMP-activated catalytic subunit beta.
     
 0.808
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.