STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPARGC1APPARG coactivator 1 alpha. (792 aa)    
Predicted Functional Partners:
PPARA
Peroxisome proliferator activated receptor alpha.
    
 0.998
PPARG
Peroxisome proliferator activated receptor gamma.
    
 0.998
SIRT1
Sirtuin 1.
    
 0.996
ENSCAPP00000017640
annotation not available
   
 0.996
NRF1
Nuclear respiratory factor 1.
    
 0.989
ESRRG
Estrogen related receptor gamma.
   
 0.986
CWC15
CWC15 spliceosome associated protein homolog.
   
 0.980
MAPK14
Mitogen-activated protein kinase 14.
    
 0.978
HNF4A
Hepatocyte nuclear factor 4 alpha.
    
 
 0.976
CREB1
cAMP responsive element binding protein 1.
    
 0.974
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.