DOT1L protein (Cavia aperea) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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Score

DOT1L

DOT1 like histone lysine methyltransferase. (1004 aa)

Predicted Functional Partners:

ENSCAPP00000000712

0.980

MLLT10

0.979

MLLT1

0.978

SETD2

0.977

ENSCAPP00000017684

0.977

ENSCAPP00000003830

0.975

ENSCAPP00000012373

0.975

MLLT6

0.974

EZH2

0.953

ENSCAPP00000011480

0.948

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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structured XML interaction data, according to the 'PSI-MI' data standard

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DOT1L	ENSCAPP00000000712	ENSCAPP00000002357	ENSCAPP00000000712	DOT1 like histone lysine methyltransferase.	annotation not available	0.980
DOT1L	ENSCAPP00000003830	ENSCAPP00000002357	ENSCAPP00000003830	DOT1 like histone lysine methyltransferase.	annotation not available	0.975
DOT1L	ENSCAPP00000011480	ENSCAPP00000002357	ENSCAPP00000011480	DOT1 like histone lysine methyltransferase.	annotation not available	0.948
DOT1L	ENSCAPP00000012373	ENSCAPP00000002357	ENSCAPP00000012373	DOT1 like histone lysine methyltransferase.	annotation not available	0.975
DOT1L	ENSCAPP00000017684	ENSCAPP00000002357	ENSCAPP00000017684	DOT1 like histone lysine methyltransferase.	annotation not available	0.977
DOT1L	EZH2	ENSCAPP00000002357	ENSCAPP00000011768	DOT1 like histone lysine methyltransferase.	Enhancer of zeste 2 polycomb repressive complex 2 subunit.	0.953
DOT1L	MLLT1	ENSCAPP00000002357	ENSCAPP00000015569	DOT1 like histone lysine methyltransferase.	MLLT1 super elongation complex subunit.	0.978
DOT1L	MLLT10	ENSCAPP00000002357	ENSCAPP00000001052	DOT1 like histone lysine methyltransferase.	MLLT10 histone lysine methyltransferase DOT1L cofactor.	0.979
DOT1L	MLLT6	ENSCAPP00000002357	ENSCAPP00000002047	DOT1 like histone lysine methyltransferase.	MLLT6, PHD finger containing.	0.974
DOT1L	SETD2	ENSCAPP00000002357	ENSCAPP00000006086	DOT1 like histone lysine methyltransferase.	SET domain containing 2, histone lysine methyltransferase.	0.977
ENSCAPP00000000712	DOT1L	ENSCAPP00000000712	ENSCAPP00000002357	annotation not available	DOT1 like histone lysine methyltransferase.	0.980
ENSCAPP00000000712	ENSCAPP00000017684	ENSCAPP00000000712	ENSCAPP00000017684	annotation not available	annotation not available	0.947
ENSCAPP00000000712	MLLT1	ENSCAPP00000000712	ENSCAPP00000015569	annotation not available	MLLT1 super elongation complex subunit.	0.997
ENSCAPP00000000712	MLLT10	ENSCAPP00000000712	ENSCAPP00000001052	annotation not available	MLLT10 histone lysine methyltransferase DOT1L cofactor.	0.943
ENSCAPP00000000712	MLLT6	ENSCAPP00000000712	ENSCAPP00000002047	annotation not available	MLLT6, PHD finger containing.	0.887
ENSCAPP00000003830	DOT1L	ENSCAPP00000003830	ENSCAPP00000002357	annotation not available	DOT1 like histone lysine methyltransferase.	0.975
ENSCAPP00000003830	ENSCAPP00000012373	ENSCAPP00000003830	ENSCAPP00000012373	annotation not available	annotation not available	0.870
ENSCAPP00000003830	ENSCAPP00000017684	ENSCAPP00000003830	ENSCAPP00000017684	annotation not available	annotation not available	0.815
ENSCAPP00000003830	EZH2	ENSCAPP00000003830	ENSCAPP00000011768	annotation not available	Enhancer of zeste 2 polycomb repressive complex 2 subunit.	0.723
ENSCAPP00000003830	SETD2	ENSCAPP00000003830	ENSCAPP00000006086	annotation not available	SET domain containing 2, histone lysine methyltransferase.	0.977