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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VANGL2VANGL planar cell polarity protein 2. (548 aa)    
Predicted Functional Partners:
PRICKLE3
Prickle planar cell polarity protein 3.
    
 0.979
PRICKLE1
Prickle planar cell polarity protein 1.
    
 0.979
DVL2
Dishevelled segment polarity protein 2.
    
 0.979
DVL1
Dishevelled segment polarity protein 1.
    
 0.959
PRICKLE2
Prickle planar cell polarity protein 2.
    
 0.955
DVL3
Dishevelled segment polarity protein 3.
    
 0.945
VANGL1
VANGL planar cell polarity protein 1.
  
 
0.944
FZD6
Frizzled class receptor 6.
    
 0.832
FZD3
Frizzled class receptor 3.
    
 0.830
WNT5A
Wnt family member 5A.
    
 0.806
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.