HIRA protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

HIRA

Histone cell cycle regulator. (931 aa)

Predicted Functional Partners:

ASF1A

0.987

ASF1B

0.976

UBN1

0.975

CABIN1

0.965

ENSCAPP00000001550

0.721

ENSCAPP00000004434

0.690

HSD17B13

0.690

DHRS3

0.690

SDR16C5

0.690

ENSCAPP00000010012

0.690

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASF1A	ASF1B	ENSCAPP00000005345	ENSCAPP00000004210	Anti-silencing function 1A histone chaperone.	Anti-silencing function 1B histone chaperone.	0.634
ASF1A	CABIN1	ENSCAPP00000005345	ENSCAPP00000004420	Anti-silencing function 1A histone chaperone.	Calcineurin binding protein 1.	0.954
ASF1A	DHRS3	ENSCAPP00000005345	ENSCAPP00000007841	Anti-silencing function 1A histone chaperone.	Dehydrogenase/reductase 3.	0.559
ASF1A	ENSCAPP00000001550	ENSCAPP00000005345	ENSCAPP00000001550	Anti-silencing function 1A histone chaperone.	annotation not available	0.958
ASF1A	ENSCAPP00000004434	ENSCAPP00000005345	ENSCAPP00000004434	Anti-silencing function 1A histone chaperone.	annotation not available	0.559
ASF1A	ENSCAPP00000010012	ENSCAPP00000005345	ENSCAPP00000010012	Anti-silencing function 1A histone chaperone.	annotation not available	0.559
ASF1A	HIRA	ENSCAPP00000005345	ENSCAPP00000002369	Anti-silencing function 1A histone chaperone.	Histone cell cycle regulator.	0.987
ASF1A	HSD17B13	ENSCAPP00000005345	ENSCAPP00000006484	Anti-silencing function 1A histone chaperone.	Hydroxysteroid 17-beta dehydrogenase 13.	0.559
ASF1A	SDR16C5	ENSCAPP00000005345	ENSCAPP00000008309	Anti-silencing function 1A histone chaperone.	Short chain dehydrogenase/reductase family 16C member 5.	0.559
ASF1A	UBN1	ENSCAPP00000005345	ENSCAPP00000014033	Anti-silencing function 1A histone chaperone.	Ubinuclein 1.	0.967
ASF1B	ASF1A	ENSCAPP00000004210	ENSCAPP00000005345	Anti-silencing function 1B histone chaperone.	Anti-silencing function 1A histone chaperone.	0.634
ASF1B	CABIN1	ENSCAPP00000004210	ENSCAPP00000004420	Anti-silencing function 1B histone chaperone.	Calcineurin binding protein 1.	0.879
ASF1B	DHRS3	ENSCAPP00000004210	ENSCAPP00000007841	Anti-silencing function 1B histone chaperone.	Dehydrogenase/reductase 3.	0.559
ASF1B	ENSCAPP00000001550	ENSCAPP00000004210	ENSCAPP00000001550	Anti-silencing function 1B histone chaperone.	annotation not available	0.958
ASF1B	ENSCAPP00000004434	ENSCAPP00000004210	ENSCAPP00000004434	Anti-silencing function 1B histone chaperone.	annotation not available	0.559
ASF1B	ENSCAPP00000010012	ENSCAPP00000004210	ENSCAPP00000010012	Anti-silencing function 1B histone chaperone.	annotation not available	0.559
ASF1B	HIRA	ENSCAPP00000004210	ENSCAPP00000002369	Anti-silencing function 1B histone chaperone.	Histone cell cycle regulator.	0.976
ASF1B	HSD17B13	ENSCAPP00000004210	ENSCAPP00000006484	Anti-silencing function 1B histone chaperone.	Hydroxysteroid 17-beta dehydrogenase 13.	0.559
ASF1B	SDR16C5	ENSCAPP00000004210	ENSCAPP00000008309	Anti-silencing function 1B histone chaperone.	Short chain dehydrogenase/reductase family 16C member 5.	0.559
ASF1B	UBN1	ENSCAPP00000004210	ENSCAPP00000014033	Anti-silencing function 1B histone chaperone.	Ubinuclein 1.	0.910